Idea votes and adoptions

Adopted

Ideas that someone outside OnCo has picked up, each with the source that shows it: a trial registration, a programme page, a funding announcement, a publication or a policy document. Recorded in src/data/adoptions.ts; nothing is inferred.

Waiting for a vote

The forty most connected ideas with no thread yet. Start one to open the vote; the first thumbs-up is yours.

• A permanently funded international network for randomised cancer surgery trialsEarly clinical · 22 connectionsDiscussstart a thread
• Core-funded radiotherapy trials infrastructure with central quality assuranceBeing tested at scale · 21 connectionsDiscussstart a thread
• Regional translational institutes with academic GMP suites and IND teamsEarly clinical · 21 connectionsDiscussstart a thread
• A dietitian in every gastrointestinal and head and neck tumour boardEarly clinical · 20 connectionsDiscussstart a thread
• GLP-1 receptor agonists as adjuvant weight-loss therapy in HR-positive breast cancerSpeculative · 20 connectionsDiscussstart a thread
• Payload-class switching as the rule for ADC sequencingPreclinical evidence · 20 connectionsDiscussstart a thread
• Link bariatric and GLP-1 registries to cancer registries in every country that has bothEarly clinical · 19 connectionsDiscussstart a thread
• Patient-level multimodal foundation models for treatment selectionPreclinical evidence · 19 connectionsDiscussstart a thread
• Capture diet, fibre and antibiotic exposure in every immunotherapy pivotal trialSpeculative · 18 connectionsDiscussstart a thread
• Confirm or refute the harm of antioxidant supplements during chemotherapyEarly clinical · 18 connectionsDiscussstart a thread
• Structured exercise prescribed like a drug in all curative-intent cancer careBeing tested at scale · 18 connectionsDiscussstart a thread
• A neutral platform trial for radiotherapy plus immunotherapy combinationsEarly clinical · 17 connectionsDiscussstart a thread
• Burden-matched funding for trials led in low- and middle-income countriesSpeculative · 17 connectionsDiscussstart a thread
• Develop drugs in children first when the target is a children's targetSpeculative · 17 connectionsDiscussstart a thread
• Group trials by broken mechanism, not by organ or single mutationEarly clinical · 17 connectionsDiscussstart a thread
• Mandatory staged registries for new surgical techniques before wide adoptionEarly clinical · 17 connectionsDiscussstart a thread
• Use pre-surgery immunotherapy windows as the field's biomarker engineBeing tested at scale · 17 connectionsDiscussstart a thread
• A non-profit pharmaceutical company for the cancers markets ignoreSpeculative · 16 connectionsDiscussstart a thread
• A ring-fenced metastasis programme with metastasis-specific endpointsSpeculative · 16 connectionsDiscussstart a thread
• A university cyclotron network with shared regulatory files for new tracersEarly clinical · 16 connectionsDiscussstart a thread
• An open-science consortium on the undruggable drivers, open until a candidateEarly clinical · 16 connectionsDiscussstart a thread
• Coverage-with-evidence registries for MR-guided and adaptive radiotherapyBeing tested at scale · 16 connectionsDiscussstart a thread
• Evaluate alcohol minimum unit pricing against cancer incidenceBeing tested at scale · 16 connectionsDiscussstart a thread
• Hospital-based CAR-T manufacturing at cost through a public networkEarly clinical · 16 connectionsDiscussstart a thread
• TROP2 PET to choose and sequence TROP2 ADCsEarly clinical · 16 connectionsDiscussstart a thread
• A dose-finding trial for exercise after cancerEarly clinical · 15 connectionsDiscussstart a thread
• A funded programme of organ-preservation trials to avoid radical surgeryBeing tested at scale · 15 connectionsDiscussstart a thread
• A single oncology trial data trust with mandatory deposit within eighteen monthsEarly clinical · 15 connectionsDiscussstart a thread
• AI quantification of HER2-low and HER2-ultralowEarly clinical · 15 connectionsDiscussstart a thread
• Burden-weighted portfolio targets for every major cancer funderSpeculative · 15 connectionsDiscussstart a thread
• Check whether a tumour can still show itself to the immune systemPreclinical evidence · 15 connectionsDiscussstart a thread
• Every tumour genomic report machine-readable and deposited nationallyEarly clinical · 15 connectionsDiscussstart a thread
• Living guidelines published as versioned, computable rulesEarly clinical · 15 connectionsDiscussstart a thread
• Molecular-progression switching beyond ESR1Early clinical · 15 connectionsDiscussstart a thread
• Oncolytic viruses that make interleukin-12 only inside the tumourEarly clinical · 15 connectionsDiscussstart a thread
• One definitive ketogenic diet trial in glioblastoma, then stopEarly clinical · 15 connectionsDiscussstart a thread
• Payers fund trials of cheaper, shorter or lower-dose versions of expensive treatmentsEarly clinical · 15 connectionsDiscussstart a thread
• Pooled coverage-with-evidence for proton therapy across all centresBeing tested at scale · 15 connectionsDiscussstart a thread
• Pre-surgery platform trials that test combinations on pathological response in monthsBeing tested at scale · 15 connectionsDiscussstart a thread
• Sequential multiple-assignment randomised trials to find the best order of ADCsSpeculative · 15 connectionsDiscussstart a thread

All ideas, filterable by maturity, actor and cost: /ideas/.