One definitive ketogenic diet trial in glioblastoma, then stop
Patients with brain tumours are sold ketogenic diets on the strength of mouse data and small feasibility studies. A single adequately powered trial with dietitian support would either prove it or let clinicians say clearly that it does not work.
Fifteen years of feasibility studies have shown ketogenic diets are tolerable for a few months in glioblastoma and have not shown efficacy. Because the diet is marketed directly to patients and is a common reason for conflict with treating teams, the cost of not knowing is high. No company will fund a diet trial; a philanthropic or cooperative-group trial with adherence biomarkers (blood ketones), a pre-registered stopping rule and a commitment to publish either way is the appropriate instrument.
- Misinformation and unproven therapies · Patients are sold unproven treatments and frightened away from proven ones.
- Failures are hidden · Negative trials, failed drugs and abandoned programmes are rarely published, so the same mistakes are repeated.
- Funding follows fashion, not burden · Money goes to the cancers and questions that are easy or popular, not the ones that kill most or where a dollar would do most.
Pages like this
not linked directly; found by shared links- IdeaAsk about diet at diagnosis, and prebunk the myths before the internet does
Shares Warburg-effect diet claims ('sugar feeds cancer'), Ketogenic diets in glioblastoma, Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Oncology nutrition assessment and medical nutrition therapy.
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Shares Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Misinformation and unproven therapies, Failures are hidden.
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Shares Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Misinformation and unproven therapies.
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Shares Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Oncology nutrition assessment and medical nutrition therapy, Misinformation and unproven therapies.
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Shares Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Misinformation and unproven therapies.
- TechnologyVitamin D and omega-3 supplementation
Shares Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Misinformation and unproven therapies, Failures are hidden.
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Shares Warburg effect, Warburg-effect diet claims ('sugar feeds cancer').