Consolidation therapy
Treatment given after a good response to kill the cancer cells that are presumably left but cannot be seen, to make the remission last. Durvalumab after chemoradiation for lung cancer is the best-known example.
In leukaemia, consolidation courses of cytarabine (or transplant) follow induction to eradicate residual disease. In lymphoma, radiotherapy to bulky sites or autologous transplant consolidates chemotherapy response; in myeloma, consolidation follows transplant before maintenance. In solid tumours the word entered common use with PACIFIC (a year of durvalumab after chemoradiation in stage III lung cancer) and ADRIATIC (durvalumab after chemoradiation in limited-stage small-cell lung cancer), and 'consolidative' SBRT or surgery to residual oligometastatic disease follows the same logic.
Pages like this
not linked directly; found by shared links- PersonJohn V. Heymach
Shares Durvalumab, Small-cell lung cancer, Non-small-cell lung cancer.
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- TrialCASPIAN
Shares Durvalumab, Small-cell lung cancer.
- TrialDeLLphi-305
Shares Durvalumab, Small-cell lung cancer.
- Term7+3 induction chemotherapy
Shares Induction therapy, Acute myeloid leukaemia.
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- TermOligoprogression