Chemoradiation (chemoradiotherapy, CRT)
Radiotherapy given at the same time as chemotherapy, which makes the radiation work better. It is the curative treatment for many cancers that cannot or should not be operated on.
Concurrent chemoradiation (usually with cisplatin, or 5-FU and mitomycin, or carboplatin-paclitaxel) is definitive treatment for cervical, anal, laryngeal and oropharyngeal cancers, stage III lung cancer (followed by durvalumab, PACIFIC), glioblastoma (with temozolomide) and bladder preservation (trimodality with TURBT), and is preoperative in oesophageal (CROSS) and rectal cancer. Concurrent beats sequential in most comparisons at the cost of more acute toxicity (mucositis, oesophagitis). Chemotherapy acts as a radiosensitiser rather than for its own systemic effect, so doses are lower than in systemic regimens.
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not linked directly; found by shared links- TermTotal mesorectal excision (TME)
Shares Abdominoperineal resection, Total neoadjuvant therapy (TNT, rectal cancer), Organ preservation (watch-and-wait, bladder-sparing, larynx preservation).
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Shares Abdominoperineal resection, Organ preservation (watch-and-wait, bladder-sparing, larynx preservation), Bladder & urothelial cancer.
- TermFeeding tube (gastrostomy, PEG, jejunostomy)
Shares Mucositis and stomatitis, Oesophageal cancer, Head and neck squamous cell carcinoma.
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Shares Mucositis and stomatitis, Oesophageal cancer, Head and neck squamous cell carcinoma.
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Shares Head and neck subsites (oral cavity, oropharynx, larynx), Cervical cancer, Head and neck squamous cell carcinoma.
- InstitutionZhejiang Cancer Hospital
Shares Oesophageal cancer, Cervical cancer, Head and neck squamous cell carcinoma, Non-small-cell lung cancer.
- TechnologySmoking cessation in cancer patients
Shares Bladder & urothelial cancer, Oesophageal cancer, Cervical cancer, Head and neck squamous cell carcinoma.
- TermHypofractionation (fewer, larger radiotherapy doses)
Shares Total neoadjuvant therapy (TNT, rectal cancer), IMRT / IGRT / VMAT (modern external beam radiotherapy).