termsTerm
Wide local excision
aka wide excision, excision margins, local excision, re-excision
Cutting out a tumour together with a measured rim of normal-looking tissue around it, so that microscopic spread at the edge is removed too.
The standard treatment for primary melanoma after diagnostic biopsy: margins of 0.5 cm for in situ, 1 cm for tumours ≤1 mm and 2 cm for thicker tumours (MSLT, MelMarT trials). The same principle applies to soft-tissue sarcomas, skin cancers, breast lumpectomy and vulval cancer. Wider is not better beyond the evidence-based margin; what matters is that the pathologist finds the edges clear (R0).
Category
Procedures
Pages like this
not linked directly; found by shared links- TermUlceration (melanoma)
Shares Breslow thickness, Melanoma.
- TechnologyLimb-salvage surgery and endoprosthetic reconstruction
Shares Limb-salvage surgery, Sarcomas (soft tissue, bone, GIST).
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Shares Breslow thickness, Melanoma.
- IdeaLet adolescents from age 12 into adult trials when the cancer biology is the same
- CompanyImmatics
- InstitutionChris O'Brien Lifehouse
- InstitutionA.C. Camargo Cancer Center
- IdeaGrow immune command posts inside tumours