Limb-salvage surgery and endoprosthetic reconstruction
Removing a bone or soft-tissue sarcoma while keeping the arm or leg, rebuilding with metal implants, bone grafts or growing prostheses in children.
Since the 1980s, >90% of extremity sarcomas are treated with limb-sparing resection plus radiotherapy (soft tissue) or chemotherapy (bone) with survival equal to amputation. Modular and expandable endoprostheses, allografts, rotationplasty, 3D-printed custom implants, and navigation-guided resection are current practice. Function and infection rates are the trade-offs.
How it works
Wide en-bloc resection with negative margins, reconstruction, and multimodal adjuvant therapy replace amputation.
- Preserves function without compromising survival
- Custom implants for pelvis and spine
- Implant infection and mechanical failure over decades
- Requires specialist sarcoma centres
Latest papers
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