Colposcopy and excisional treatment (LEEP/LLETZ, cone)
Looking at the cervix with a magnifier after a positive screen, then removing the abnormal patch with an electric wire loop in a clinic visit.
Colposcopy with acetic acid and biopsy confirms high-grade lesions; LEEP/LLETZ or cold-knife conisation removes them with cure rates above 90%. Excision slightly raises preterm birth risk, which drives interest in ablation and in 'see-and-treat' for HSIL. AI-assisted colposcopy is being validated for settings without specialists.
How it works
Magnified inspection with contrast agents to target biopsy, followed by electrosurgical excision of the transformation zone.
- Outpatient, definitive histology
- High cure rate
- Requires trained providers and equipment
- Obstetric risk after excision
Latest papers
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Pages like this
not linked directly; found by shared links- TechnologyThermal ablation and cryotherapy for cervical precancer
Shares Cervical precancer (CIN, HSIL/LSIL), Basement membrane & tissue barriers, HPV DNA testing and self-sampling, Cervical cancer.
- PersonPartha Basu
- PersonHarald zur Hausen
Shares Cervical precancer (CIN, HSIL/LSIL), HPV DNA testing and self-sampling, Cervical cancer.
- InstitutionUniversity of New Mexico Comprehensive Cancer Center
- PersonHenrietta Lacks
- PathwayField cancerisation
Shares Cervical precancer (CIN, HSIL/LSIL), Basement membrane & tissue barriers, Cervical cancer.
- InstitutionBC Cancer
- Key paperEngland's HPV programme: cervical cancer down 87% in the first cohort vaccinated at 12-13