Hospital Clínic de Barcelona / IDIBAPS

Hospital Clínic and its research institute IDIBAPS form one of Spain's strongest academic medical centres. The Barcelona Clinic Liver Cancer group of Jordi Bruix and Josep Maria Llovet created the BCLC staging and treatment algorithm and led the SHARP trial that made sorafenib the first systemic therapy for hepatocellular carcinoma. Elías Campo's group mapped the genome of chronic lymphocytic leukaemia within the ICGC and co-edits the WHO haematolymphoid classification, Aleix Prat's group advanced intrinsic subtyping (PAM50, HER2DX) in breast cancer, and the hospital's ARI-0001 CD19 CAR-T, developed by Manel Juan and Álvaro Urbano-Ispizua, became the first academic CAR-T authorised in Europe under Spain's hospital exemption in 2021. The centre is OECI-accredited and runs a large early-phase and haematology programme.