Test whether calling Gleason 6 'not cancer' changes what men choose
Gleason 6 prostate lesions do not metastasise. A trial could show whether describing them without the word cancer leads more men to choose monitoring.
Survey experiments show terminology shifts preference; no randomised trial has tested it in real diagnoses. Propose a trial embedded in diagnostic clinics: pathology report and consultation script using 'cancer' versus 'indolent lesion of epithelial origin', with active surveillance uptake, anxiety, and two-year treatment as endpoints.
- Overdiagnosis and false alarms · Finding more cancer is not the same as saving lives. Screening also finds cancers that would never have hurt anyone, and treats them.
- Patients lack understanding, navigation and agency · Most patients cannot understand their options, find trials, or push back, so decisions are made for them.
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not linked directly; found by shared links- IdeaCertified decision aids required for every preference-sensitive cancer decision
Shares Overdiagnosis and false alarms, Patients lack understanding, navigation and agency, Prostate cancer.
- IdeaModern autopsy studies to measure how much silent cancer people carry
- IdeaDecision aids built into the record for every preference-sensitive cancer choice
Shares Patients lack understanding, navigation and agency, Prostate cancer.
- IdeaAn international body to rename indolent lesions so 'cancer' means something
- TrialPRECISION
- TermGleason score / Grade Group
- IdeaProstate active surveillance without scheduled biopsies: MRI and blood tests decide
- IdeaA mandatory decision aid before any multi-cancer blood test
Shares Overdiagnosis and false alarms, Patients lack understanding, navigation and agency.