OnCo
ideasIdea

Toxicity-management decision support for nurses and pharmacists

Give the nurses and pharmacists who take patients' calls a tool that walks them through recognising and managing side effects of modern cancer drugs, including when to escalate.

Immunotherapy and targeted therapy toxicities are managed by triage nurses and pharmacists who may see a given drug rarely. Guideline-based toxicity algorithms (ESMO, ASCO, SITC) exist as tables. Encoding them as decision support integrated with ePRO alerts, with drug-specific pathways and escalation triggers, would standardise management and shorten time to steroids or hospital review for serious immune-related events.

Hypothesis
Toxicity CDS will reduce time from symptom report to appropriate management and cut hospital admissions for grade 3 or higher immune-related adverse events by a meaningful margin.
Rationale
Delayed recognition of immune-related adverse events is a documented cause of morbidity; nurse-led triage with structured pathways has reduced admissions in single-centre studies.
What would test it
Deploy across a cancer network's triage lines for one year; compare admissions for immune-related events and time to intervention with the prior year and matched networks.
Maturity
early clinical
Who has to act
clinic
Cost to try
Small (under $1M)
Years to first evidence
2
Bottlenecks it attacks

Connected

8top

Pages like this

not linked directly; found by shared links