University Cancer Center Mainz (UCT Mainz) / Universitätsmedizin Mainz
The university medical centre where Uğur Şahin and Özlem Türeci built the science behind BioNTech and personalised mRNA cancer vaccines.
Universitätsmedizin Mainz is the home institution of Uğur Şahin and Özlem Türeci, who founded BioNTech in Mainz in 2008 and the translational institute TRON in 2010 to pursue individualised neoantigen mRNA vaccines, the concept later tested as autogene cevumeran with Genentech. The Helmholtz Institute for Translational Oncology (HI-TRON), a DKFZ partnership, and the UCT Mainz make the site a German Cancer Aid Oncology Center of Excellence and DKTK partner. Clinical strengths include haematology, dermato-oncology (a large melanoma trial site for BioNTech's programmes), neuro-oncology and the Mainz Research Center for Immunotherapy (FZI). The city has become a hub for mRNA and immunotherapy companies around the university.
- Individualised mRNA cancer vaccines (TRON, BioNTech)
- HI-TRON Mainz
- Research Center for Immunotherapy
- Melanoma
- Haematology
Pages like this
not linked directly; found by shared links- IdeaPersonalised vaccines given only when the blood test turns positive
Shares BioNTech, Autogene cevumeran, Neoantigen, Personalised neoantigen (mRNA) vaccines.
- IdeaPersonalised cancer vaccines at commodity cost through fully automated manufacturing
Shares BioNTech, Autogene cevumeran, Neoantigen, Personalised neoantigen (mRNA) vaccines.
- Key paperRojas 2023: a personalised mRNA vaccine trained T cells against each patient's pancreatic cancer, and those who responded stayed cancer-free longer
Shares BioNTech, Autogene cevumeran, Neoantigen, Personalised neoantigen (mRNA) vaccines.
- PairingPersonalised neoantigen vaccine + PD-1 blockade
Shares Autogene cevumeran, Personalised neoantigen (mRNA) vaccines, Melanoma, Pancreatic ductal adenocarcinoma.
- IdeaVaccines aimed only at mutations shared by every tumour cell
Shares BioNTech, Neoantigen, Personalised neoantigen (mRNA) vaccines.
- IdeaWhat makes a neoantigen actually immunogenic?
Shares Autogene cevumeran, Neoantigen, Personalised neoantigen (mRNA) vaccines.
- TargetEpCAM
Shares Bispecific antibodies, CAR-T cell therapy, Pancreatic ductal adenocarcinoma, Colorectal cancer.
- InstitutionComprehensive Cancer Center Tübingen-Stuttgart
Shares German Cancer Research Center (DKFZ), Neoantigen, Personalised neoantigen (mRNA) vaccines, Melanoma.