Sanford Burnham Prebys Medical Discovery Institute
La Jolla research institute and NCI basic cancer centre, birthplace of integrin and RGD-peptide biology and home to a major academic drug-screening centre.
Founded in 1976 by Erkki Ruoslahti as the La Jolla Cancer Research Foundation and NCI-designated since 1981, Sanford Burnham Prebys is a basic laboratory cancer centre whose founding discoveries in integrins and RGD adhesion peptides created the field of tumour-homing peptides. The Conrad Prebys Center for Chemical Genomics is one of the largest non-profit drug discovery and high-throughput screening facilities in academia. Current programmes span cancer metabolism, the tumour microenvironment and immune evasion, paediatric cancers and computational biology. The institute works alongside Salk, Scripps and UC San Diego on the Torrey Pines mesa.
- Drug discovery (Prebys Center)
- Cell adhesion and tumour microenvironment
- Cancer metabolism
Pages like this
not linked directly; found by shared links- InstitutionSalk Institute Cancer Center
Shares UC San Diego Moores Cancer Center, Cold tumours and the immunosuppressive microenvironment.
- IdeaDrag cancer's surface and secreted proteins to the cell's recycling bin
Shares Cold tumours and the immunosuppressive microenvironment, The undruggable drivers.
- IdeaA drug screen that only rewards killing sleeping cancer cells
Shares Functional (ex vivo) drug testing, The undruggable drivers.
- IdeaImplant a tiny device that tests twenty drugs inside the patient's own tumour
Shares Functional (ex vivo) drug testing, Cold tumours and the immunosuppressive microenvironment.
- IdeaEngineered bacteria that live in tumours and manufacture drugs there
Shares Cold tumours and the immunosuppressive microenvironment, The undruggable drivers.
- Key paperNAPOLI-3: NALIRIFOX versus gemcitabine plus nab-paclitaxel as first treatment for metastatic pancreatic cancer
Shares Cold tumours and the immunosuppressive microenvironment, The undruggable drivers.
- Key paperDefining a Cancer Dependency Map: which genes each cancer cell line cannot live without
Shares Functional (ex vivo) drug testing, The undruggable drivers.
- InstitutionWellcome Sanger Institute
Shares Functional (ex vivo) drug testing, The undruggable drivers.