Offer everyone at 30 a test for the cancer genes that matter
Most people with BRCA or Lynch mutations do not know until they get cancer. Testing everyone once for a short list of high-impact genes would find them in time to prevent it.
Population screening for CDC Tier 1 conditions (BRCA1/2, Lynch syndrome, familial hypercholesterolaemia) has been piloted in Geisinger MyCode, the Healthy Nevada Project, and Jewish BRCA programmes, finding that most carriers would not meet family-history criteria. Propose a national programme at age 30 with tiered disclosure and linked prevention pathways.
- Inherited risk is mostly unidentified · Most people who carry a high-risk cancer gene do not know it until they or a relative gets cancer.
Pages like this
not linked directly; found by shared links- IdeaA bone drug to prevent breast cancer in BRCA1 carriers
Shares PROSE consortium: preventive surgery lowers cancer and death in BRCA1 and BRCA2 carriers, Inherited risk is mostly unidentified, BRCA1 / BRCA2 (HRD).
- IdeaGo back to families of women who died of ovarian cancer and offer BRCA testing
Shares Inherited risk is mostly unidentified, BRCA1 / BRCA2 (HRD), Germline (hereditary) testing.
- IdeaLet clinics contact relatives directly when a cancer gene is found
Shares Inherited risk is mostly unidentified, BRCA1 / BRCA2 (HRD), Germline (hereditary) testing.
- IdeaPopulation germline screening for hereditary cancer genes with cascade testing
Shares PROSE consortium: preventive surgery lowers cancer and death in BRCA1 and BRCA2 carriers, Inherited risk is mostly unidentified, BRCA1 / BRCA2 (HRD), Germline (hereditary) testing.
- IdeaFamily history collected by app and matched to testing criteria automatically
Shares Inherited risk is mostly unidentified, Germline (hereditary) testing.
- IdeaBan life and disability insurers from using genetic results
Shares Inherited risk is mostly unidentified, Germline (hereditary) testing.
- IdeaBuild polygenic scores that work in every ancestry before deploying any
Shares Inherited risk is mostly unidentified, Germline (hereditary) testing.
- IdeaStore adult-onset cancer gene results from newborn genomes and disclose at 18
Shares Inherited risk is mostly unidentified, Germline (hereditary) testing.