Store adult-onset cancer gene results from newborn genomes and disclose at 18
Newborn sequencing programmes exclude adult cancer genes because babies cannot consent. Storing those results and offering them at 18 would preserve choice and give a lifetime of prevention.
Genomics England's Generation Study sequences newborns for childhood-onset conditions only. Propose a consented pathway in which adult-onset actionable variants (BRCA, Lynch) are sequestered and offered for disclosure at 18 with counselling.
- Inherited risk is mostly unidentified · Most people who carry a high-risk cancer gene do not know it until they or a relative gets cancer.
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- IdeaGo back to families of women who died of ovarian cancer and offer BRCA testing
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Shares Inherited risk is mostly unidentified, Whole-exome & whole-genome sequencing, Germline (hereditary) testing.