OnCo
ideasIdea

Living, machine-readable guidelines pushed to the point of care in every country

Cancer treatment guidance changes constantly and takes years to reach many clinics. Make guidelines live documents that software can read, updated as evidence arrives and adapted to what each country can afford.

Guidelines are published as prose, updated on annual cycles, and adapted slowly for resource-limited settings; diffusion of practice-changing evidence takes years. The proposal is a shared open format for computable guidelines (eligibility, options, evidence grades, resource tiers), a living update process triggered by trial results, and integration into electronic prescribing and decision support so that every treatment plan is checked against current, resource-appropriate guidance, with feedback on concordance by country and centre.

Hypothesis
Computable living guidelines cut the median time from practice-changing trial to routine use from years to months and raise guideline concordance in participating low- and middle-income centres.
Rationale
Knowledge diffusion fails at the last mile; software can carry the update to every prescriber, and resource tiering (as NCCN Harmonized Guidelines began) makes the guidance applicable.
What would test it
Implement for three cancers across twenty centres in five countries; measure time to adoption of new evidence and concordance before and after.
Maturity
early clinical
Who has to act
data
Cost to try
Medium ($1M to $50M)
Years to first evidence
3
Bottlenecks it attacks

Connected

6top

Pages like this

not linked directly; found by shared links