Blood-based HCC surveillance to replace six-monthly ultrasound
A blood test (methylation, GALAD) that finds liver cancer early in people with cirrhosis, especially those with fatty liver where ultrasound fails.
Ultrasound misses a third of early HCC in obese and steatotic livers. cfDNA methylation panels and the GALAD score reach sensitivities of 70-85% for early-stage disease in case-control studies; prospective surveillance cohorts are underway.
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not linked directly; found by shared links- CompanyHarbinger Health
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- InstitutionPrince of Wales Hospital / Chinese University of Hong Kong
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