OncoKB
Tells you, for a given mutation, whether an approved or investigational drug exists and how strong the evidence is.
FDA-recognised human variant database (2021). Levels 1-4 and R1-R2 for resistance. API available; used by cBioPortal and many molecular tumour boards.
Pages like this
not linked directly; found by shared links- CollectionCIViC
Shares Label every biomarker claim with an evidence phase, like drugs, Cancer variant knowledgebases and molecular tumour boards, An open knowledge graph linking trials, results, biomarkers, drugs and recommendations, Clinical NGS bioinformatics and variant interpretation.
- CollectioncBioPortal for Cancer Genomics
Shares Cancer variant knowledgebases and molecular tumour boards, Clinical NGS bioinformatics and variant interpretation, Every tumour genomic report machine-readable and deposited nationally, Pool every immunotherapy trial's biomarker data into one commons.
- IdeaDecision support that cites the exact trial and guideline line it relies on
Shares A tumour board assistant that cites its evidence and tracks outcomes, An open knowledge graph linking trials, results, biomarkers, drugs and recommendations, Knowledge reaches practice too slowly.
- CompanyCaris Life Sciences
Shares Every tumour sequencing report lists open, nearby, matched trials pulled live, Every tumour genomic report machine-readable and deposited nationally, Comprehensive genomic profiling.
- IdeaA randomised trial of AI-generated treatment recommendations versus tumour boards
Shares A tumour board assistant that cites its evidence and tracks outcomes, Knowledge reaches practice too slowly.
- IdeaA public API serving the current standard of care for any cancer, stage and biomarker
Shares An open knowledge graph linking trials, results, biomarkers, drugs and recommendations, Knowledge reaches practice too slowly.
- CollectionAACR Project GENIE
Shares Every tumour genomic report machine-readable and deposited nationally, Pool every immunotherapy trial's biomarker data into one commons, Check whether a tumour can still show itself to the immune system.
- TermNext-generation sequencing (NGS)
Shares Every tumour sequencing report lists open, nearby, matched trials pulled live, Every tumour genomic report machine-readable and deposited nationally, Comprehensive genomic profiling.