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Whole-slide scanners and image management

The scanners that turn glass slides into gigapixel images, and the software that stores and serves them, without which pathology AI cannot run.

Leica Biosystems (Aperio GT 450), Hamamatsu (NanoZoomer), 3DHISTECH (Pannoramic), Philips (IntelliSite; FDA-cleared for primary diagnosis 2017), Roche (VENTANA DP 600), and Grundium supply scanners; Sectra, Philips, Proscia (Concentriq), PathAI (AISight), Indica Labs (HALO), and Paige provide image management and viewing. Interoperability (DICOM-WSI) and storage costs (1-4 GB per slide) are the practical constraints on going fully digital.

Generic schematic · not to scale · placeholder for the diagnostics front
Molecular read-out

How it works

Automated microscopy tiles a slide at 20-40x, then stitches and compresses it into a pyramidal image; image management platforms index, stream, and integrate with LIS/EHR and AI.

Strengths
  • Remote sign-out, second opinions, AI-ready archives
Limitations
  • Storage and network cost
  • Scanner-to-scanner colour and focus variation affects AI
  • Workflow change management

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