Hyperthermia
Hyperthermia heats tumours to 40-43 °C to make radiation and chemotherapy work better.
Regional and deep hyperthermia improve outcomes with radiotherapy in cervical cancer, recurrent breast cancer, and soft-tissue sarcoma (EORTC 62961). Magnetic nanoparticle hyperthermia (NanoTherm) is approved in Europe for glioblastoma. Underused outside Germany and the Netherlands.
How it works
Heat impairs DNA repair and increases perfusion and drug delivery.
- Radiosensitiser without added toxicity
- Equipment and expertise scarce
Latest papers
topQuery for this technology: (TITLE:"hyperthermia" OR ABSTRACT:"hyperthermia") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma) AND (radiotherapy OR chemotherapy). Results are unfiltered search hits about Hyperthermia, not a curated reading list.