peoplePerson
Olivier Delattre
Olivier Delattre discovered the EWS-FLI1 fusion that defines Ewing sarcoma.
Olivier Delattre identified the EWSR1-FLI1 gene fusion in Ewing sarcoma in 1992 and has led paediatric cancer genomics and the Institut Curie research centre.
Role
Director, Research Center, Institut Curie; Head, Genetics and Biology of Cancers
Institution
Specialisms
Paediatric sarcomaEwing sarcoma geneticsCancer genomics
Profiles
| Title | Journal | Year |
|---|---|---|
| Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours | Nature | 1992 |
Pages like this
not linked directly; found by shared links- IdeaDegraders for the fusion proteins that drive childhood sarcomas
- IdeaThe pathology lab triggers a trial referral the day a rare cancer is diagnosed
- TermSarcoma (tissue type)
- ProductCrizotinib
- ProductLarotrectinib
- TargetEWSR1-FLI1 fusion
- ProductEntrectinib
- IdeaGroup trials by broken mechanism, not by organ or single mutation