A global open trials operating system any hospital can plug into
Build the shared software, legal templates and data standards that let any hospital in the world join a cancer trial in weeks instead of years, the way the internet let any computer join the network.
Trial start-up takes many months per site because every sponsor, country and hospital reinvents contracts, ethics submissions, data capture and monitoring. The proposal is an open-source, openly governed trials operating system: standard master agreements, a single global ethics dossier format accepted by participating regulators, e-consent and eligibility modules, mCODE-based data capture from electronic records, risk-based remote monitoring and open protocol templates, with certification of sites and a fund to connect hospitals in low- and middle-income countries.
- Trials enrol too few, too slowly · Fewer than one in ten adults with cancer joins a trial. Trials close for lack of patients, not lack of ideas.
- Regulatory divergence between regions · Regulatory divergence means a drug approved in one country can take years to reach another, or never arrive.
- Trials do not represent the people who get cancer · Older, Black, Hispanic, Asian, rural, poor and multimorbid patients are under-represented, so results may not apply to them.
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not linked directly; found by shared links- IdeaPay trial participants for their time, not only their expenses
Shares Trials do not represent the people who get cancer, Trials enrol too few, too slowly.
- IdeaTravel, lodging and meals reimbursed as a standard line in every trial budget
Shares Trials do not represent the people who get cancer, Trials enrol too few, too slowly.
- IdeaPatients are told which trials they qualify for at every treatment decision, in writing
Shares AI trial matching & clinical decision support, Trials enrol too few, too slowly.
- IdeaCommunity health workers and trusted local organisations paid to recruit for trials
Shares Trials do not represent the people who get cancer, Trials enrol too few, too slowly.
- IdeaAt least a third of pivotal-trial sites in community and rural settings
Shares Trials do not represent the people who get cancer, Trials enrol too few, too slowly.
- IdeaRemove blanket exclusions for mental illness and dementia; support consent instead
Shares Trials do not represent the people who get cancer, Trials enrol too few, too slowly.
- IdeaMobile research units bring trial visits to rural towns
Shares Trials do not represent the people who get cancer, Trials enrol too few, too slowly.
- IdeaDrop the 'must speak English' rule: translated consent and questionnaires as standard
Shares Trials do not represent the people who get cancer, Trials enrol too few, too slowly.