Accredited trusted research environments with curated cancer tables
Secure online workrooms where approved researchers can analyse cancer records without downloading them, with the data already cleaned and organised for cancer questions.
Trusted research environments (TREs) under the Five Safes model are now the default in the UK (NHS Secure Data Environments, OpenSAFELY) and emerging elsewhere. What is missing for oncology is curation: standardised, documented cancer tables (diagnosis, stage, treatment lines, response, death) refreshed on a schedule, so every study does not rebuild them. The proposal funds a small curation team per TRE and an accreditation standard for cancer-ready TREs.
- Data silos · Records, scans, genomes and outcomes sit in separate systems that cannot talk. Every patient's experience is lost to the next.
- Preclinical results do not reproduce · Fewer than half of landmark cancer biology findings reproduce when someone else tries.
Pages like this
not linked directly; found by shared links- IdeaNo mCODE, no payment: tie oncology reimbursement to a minimal structured record
Shares Real-world evidence, Data silos.
- IdeaPre-registration and results reporting for real-world cancer studies
Shares Preclinical results do not reproduce, Real-world evidence.
- IdeaPoint-of-care randomisation built into the oncology record
Shares Real-world evidence, Data silos.
- IdeaOpen, benchmarked algorithms for lines of therapy and progression from routine data
Shares Real-world evidence, Data silos.
- IdeaEnforce individual participant data sharing as a condition of publication and funding
- IdeaAutomatic weekly linkage of cancer registries to deaths, prescriptions and imaging
Shares Real-world evidence, Data silos.
- IdeaSend the code to the data: a federated analytics network of cancer centres
Shares Real-world evidence, Data silos.
- IdeaA global federated real-world evidence network at regulatory grade
Shares Real-world evidence, Data silos.