OnCo
termsTerm

CA 19-9

A sugar molecule shed into the blood by most pancreatic cancers; useful to follow treatment, not to screen.

Sialyl-Lewis A carbohydrate antigen elevated in ~80% of PDAC; 5-10% of people (Lewis-negative) cannot make it. Prognostic at diagnosis, tracks response and recurrence, and defines eligibility in trials. Too non-specific for population screening (raised in biliary obstruction, pancreatitis), but glycan-engineered variants and combination with cfDNA are under study for high-risk surveillance.

Biomarkers: what this kind of term is about · animated schematic, not to scale
Category
Biomarkers

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