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Genomics cloud and secure research environments

Cloud systems where hospitals and researchers store and analyse genomic data securely at petabyte scale.

DNAnexus (UK Biobank RAP, Genomics England), Velsera/Seven Bridges (NCI Cancer Genomics Cloud), Terra (Broad/Verily; AnVIL), Lifebit, and the hyperscalers' genomics services host data and workflows under controlled access; trusted research environments (Genomics England, UK Biobank, NIH dbGaP, EGA, GDC) implement 'data visiting' rather than download. Interoperability standards (GA4GH Passports, DRS, WES) enable federated analysis across national resources.

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Flagged finding · Neural network

How it works

Object storage plus containerised workflow engines (WDL, Nextflow, CWL) in access-controlled cloud tenancies with audit and egress controls.

Strengths
  • Scale and reproducibility
  • Controlled sharing of sensitive data
Limitations
  • Cloud cost
  • Jurisdictional data-residency rules
  • Vendor lock-in

Latest papers

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Query for this technology: (TITLE:"Genomics cloud and secure research environments" OR ABSTRACT:"Genomics cloud and secure research environments") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Genomics cloud and secure research environments, not a curated reading list.

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