peoplePerson
Hans-Gustaf Ljunggren
Hans-Gustaf Ljunggren proposed the missing-self hypothesis of NK cell recognition.
Hans-Gustaf Ljunggren, with Klas Kärre, formulated the missing-self hypothesis explaining how NK cells attack cells lacking MHC class I, a foundation for NK-based cancer immunotherapy.
Role
Professor of Infectious Medicine, Karolinska Institutet; Center for Infectious Medicine
Institution
Specialisms
NK cell biologyMissing-self recognitionCell therapy
Profiles
| Title | Journal | Year |
|---|---|---|
| In search of the 'missing self': MHC molecules and NK cell recognition | Immunology Today | 1990 |