City of Hope
Los Angeles cancer centre where synthetic insulin and humanised antibodies were developed; a CAR-T manufacturing leader.
IL13Rα2 CAR-T for glioblastoma (Brown, Badie), in-house cell manufacturing, transplant; acquired Cancer Treatment Centers of America.
- CAR-T for glioma
- Transplant
Led the SWOG S1826 trial that made nivolumab part of first-line Hodgkin lymphoma treatment.
Neurosurgeon who delivers CAR-T cells directly into the brain in City of Hope's glioma trials.
Engineered the IL13Rα2 CAR-T cells that produced a complete response in glioblastoma when infused into the brain.
Breast oncologist who led key ADC and CDK4/6 trials and moved from UCSF to City of Hope in 2024.
Michael Caligiuri is an NK cell immunologist and past AACR president who leads City of Hope's hospital.
Leads City of Hope, which expanded into a national cancer system with the acquisition of Cancer Treatment Centers of America.
Transplant pioneer who built City of Hope's cell therapy programme, one of the largest in the country.
Steven Rosen is a lymphoma specialist who directs City of Hope's research enterprise.
Virginia Sun is a nurse scientist who leads SWOG's supportive care and survivorship research.