OnCo
ideasIdea

One national master contract and budget template for all cancer trials

Contract negotiation between a hospital and a drug company often takes longer than the trial's first patient. A single pre-agreed contract and budget template, used by everyone, would cut months off opening a trial.

A government or national research body publishes a non-negotiable model clinical trial agreement (the UK's model agreements and Accelerated Clinical Trial Agreement are precedents) plus a standard per-procedure budget schedule. Sites and sponsors that adopt it skip legal negotiation; adopters are listed publicly and public funders require adoption. Extend the same to a standard data-sharing clause and a standard indemnity.

Hypothesis
Countries or networks adopting a mandatory model agreement will reduce median site activation time by at least 60 days and increase the number of sites opened per trial.
Rationale
UK sites using the model agreement report shorter set-up; the variance in contracts adds cost without protecting anyone. Standardisation of routine legal instruments has worked in property, finance and open-source licensing.
What would test it
Compare median site activation time and sites-per-trial in networks before and after mandatory adoption, using registry-recorded activation dates.
Maturity
early clinical
Who has to act
policy
Cost to try
Small (under $1M)
Years to first evidence
2
Bottlenecks it attacks

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