[{"id":"idea-bio1-translation-dependency-myc","kind":"idea","name":"Starve MYC-driven tumours by blocking protein production machinery","route":"/ideas/idea-bio1-translation-dependency-myc/","commit":"0bdbdae6c6","date":"2026-09-09","author":"Jude Gomila","message":"Editing pass: every TL;DR and summary stands alone","file":"src/data/ideas-waves/wave-biology-1.ts","type":"changed","fields":[{"field":"rationale","before":"\"This is an indirect route to MYC that requires no MYC binder; the dependency is well supported in models, but trials to date have largely been unselected, which is a common reason such drugs fail.\"","after":"\"Blocking translation is an indirect route to MYC that requires no MYC binder; the dependency is well supported in models, but trials to date have largely been unselected, which is a common reason such drugs fail.\""}]},{"id":"idea-bio1-translation-dependency-myc","kind":"idea","name":"Starve MYC-driven tumours by blocking protein production machinery","route":"/ideas/idea-bio1-translation-dependency-myc/","commit":"ec38dbcf9c","date":"2026-09-08","author":"Jude Gomila","message":"Ideas wave: tumour biology, part 1","file":"src/data/ideas-waves/wave-biology-1.ts","type":"added","fields":[{"field":"id"},{"field":"name"},{"field":"maturity"},{"field":"tldr"},{"field":"summary"},{"field":"hypothesis"},{"field":"rationale"},{"field":"test"},{"field":"actor"},{"field":"cost"},{"field":"horizonYears"},{"field":"bottlenecks"},{"field":"cancers"},{"field":"terms"}]}]